Further Resources on DNA
Send suggestions to
Eric Martz.
- BioMolecular Explorer 3D
- includes this entire DNA website, plus other popular molecules
with resources for High School Teachers. Available online, or
on a CD. The CD saves time by including the installers
for the Chime plugin and the Netscape
4.8 browser, and is ideal for teachers with limited access to high speed
Internet connections.
-
Exploring DNA Structure
- An introduction to DNA Structure for high school students,
by Andrew Carter, for the 50th Anniversary of the double helix.
Introduces coloring schemes and representations, building blocks (nucleotides,
bases, deoxyribose, phosphate). Animation of building a strand from individual nucleotides.
Cartoon of the central dogma (DNA -> mRNA -> protein). Animation of
strand separation and replication. Bending of DNA by proteins and the
nucleosome. Requires the free MDL Chime
browser plugin. Works in Internet Explorer!
-
Putting DNA To Work
- At the Marian Koshland Science Museum of the National
Academy of Sciences: includes basic DNA science, diseases,
forensics, crops, with flash animations.
Resources for teachers and students.
-
Explore IT Gene Hunter
- An introduction to DNA for high school students,
by Todd Nickle at Mount Royal College, Alberta, Canada.
Includes Flash animations, an introduction to BLAST sequence
searching, and a DNA-o-gram message encoder and decoder.
-
DNA Interactive
(www.dnai.org)
-
Resources for teachers and students (high school and up), including
a DNA timeline, discovery of the code, interactive introductions to
techniques, genomics, applications, and video clips.
- MyDNA
-
The MyDNA Project provides information on DNA for
lay-persons, including human interest stories, interactive
Discovery
Modules,
(simulations of agarose gel electrophoresis and
restriction-- requires Shockwave player), and links to other
resources. In addition, the website links to a college
freshman-level course at the University of Massachusetts designed
by Molly Fitzgerald-Hayes and Frieda Reichsman, the developers of
the MyDNA Project.
DNA Construction and Discovery Model Kit
-
available from
3D Molecular Designs,
pioneers in macromolecular models for education and research.
DNA Sculpture
-
Sculptor
Bathsheba Grossman makes "laser crystals" in which the
macromolecule (DNA double helix shown at right) is
represented by tiny laser-induced fractures within a glass block.
Other macromolecular sculptures and physical models.
-
DNA History: Deciphering the Genetic Code - Marshall Nirenberg
-
from the
DeWitt Stetten, Jr., Museum of Medical Research at the National
Institutes of Health.
-
DNA History: 50th Anniversary of the Discovery of DNA Structure.
-
DNA Day: A list of links to 50th anniversary sites.
provided by the
RCSB Protein Data Bank.
- The World Index of Molecular
Visualization Resources
-
lists many tutorials on DNA, RNA, and protein-nucleic acid complexes,
as well as sources of atomic coordinate files (PDB files) for
them. Notable among these are:
- Exploring DNA Structure
(available in English and Italian)
by Frieda Reichsman. Here you will also find tutorials on
Restriction Enzymes: Eco RV,
Hammerhead Ribozyme,
and
DNA-Binding Motifs among others.
- DNA polymerases, recombinases, integrases, repressors and repair
proteins at David Marcey's
Online Macromolecular Museum.
- Generate DNA double helices of any length (B form or A form)
from any sequence you specify.
-
The
Atlas of Macromolecules
- enables you to
explore the structures of various forms of DNA, RNA, and protein-nucleic acid complexes
in Protein Explorer.
-
An Introduction to Nucleic Acids
-
by Helen Berman at the
Nucleic Acids Database (NDB), Rutgers U.
-
Atlas of Nucleic Acid-Containing Structures
-
of the
NDB
contains images and atomic coordinate files for various states of
A-, B-, and Z-DNA, also RNA, nucleic-acid:protein complexes, etc.
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